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I graduated from the University of Nottingham, UK, with BEng in Electronics Engineering, 2000. Later I completed my PhD in the National University of Singapore, 2004.
The main research topic of my PhD work was in the design of scheduling algorithms in parallel and distributed systems. The work mainly focused on the design of scheduling strategies, using Divisible Load Theory (DLT), for divisible loads or tasks that are computationally intensive. I considered the design and analysis of load distribution strategy in generic scenarios but later, I expanded the work to specific scheduling problems in the field of bioinformatics.
After I graduated, I joined the Network Storage Technology (NST) lab of the Data Storage Institute (DSI), part of the Singapore Agency for Science, Technology and Research (A*STAR) (key agency research development for the Singapore government). I was involved in the pilot project of design, research and development of a dynamic Grid storage resource allocation infrastructure. In our design, we considered the Storage Management Initiative Specifications (SMI-S) that simplify the management of heterogeneous storage systems/devices, such that devices can be added, replace, or migrate from one server to another with minimal or no reconfiguration at all.
Later, I joined the University of Exeter, UK, on project with the University of Manchester. The project, referred to as e-fungi, has the primary aim of developing a data warehouse that integrates sequence and functional data from multiple fungal sequences in a way that facilitates the systematic study and analysis of species with reference to model organisms that have been more fully explored in terms of functional characteristics. More information can be found on the e-fungi official page.
In 2008, I went to the University of Cambridge to research quadruplex sequences in the human genome. Quadruplex sequences, also known as G-quadruplex, are sequences that are able to form the 'interesting' G-tetrad structure. These sequences, prevalent in promoter regions, have been found to have gene regulating functions. Further, due to their unique structure, quadruplex sequences are especially good candidates for drug targets. During those years, I have identify list of quadruplex targets for cancer related genes, showed the associations of quadruplex with nucleosomes, presented the characteristics of nucleosome by means of evolutions, etc. I have also extebded various tools for the web-based quadruplex research community. These tools and other details can be found in Quadruplex.org
I am currently working in an investment bank as a developer, working in a totally different realm of finance. The project that I am currently in involve extending a electronic transaction system that provides vital information backfeed to the clients for processing in their decision making process.
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